PREVALENCE OF IRON DEFICIENCY ANEMIA IN
NON-DIALYSIS-DEPENDENT CHRONIC KIDNEY DISEASE

Anemia presents as a serious and common complication in the early stages of NDD-CKD, and progressively worsens as renal function declines. Studies show a strong association between a progressive decline in hemoglobin and increased CKD severity.1
Large scale population studies show that the prevalence of anemia within NDD-CKD is <10% in CKD Stages 1 and 2, 20–40% in Stage 3, and 50–60% in Stage 4. Anemia is even more prevalent in stage 5 dialysis-dependent CKD.1
Anemia presents as a serious and common complication in the early stages of NDD-CKD, and progressively worsens as renal function declines. Studies show a strong association between a progressive decline in hemoglobin and increased CKD severity.1

15.4% NDD-CKD
with anemia

85.6% NDD-CKD
without anemia

Figure: Prevalence of anemia in patients with NDD-CKD2
CKD affects an estimated 15% of U.S. adults or 37 million people, with the vast majority being NDD-CKD.2 Studies show that 15.4% of patients with CKD in the U.S. have anemia. This represents more than 5 million people in the U.S. who have anemia and NDD-CKD, with a large proportion of these patients suffering from iron-deficiency anemia (IDA).3

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REFERENCES:

  1. Vikrant S. Etiological spectrum of anemia in non-dialysis-dependent chronic kidney disease: A single-center study from India. Saudi J Kidney Dis Transpl. 2019;30(4):932-942.
    doi:10.4103/1319-2442.265471

  2. Center for Disease Control and Prevention (CDC) website. Kidney Disease. Date accessed August 2022. https://www.cdc.gov/kidneydisease/publications-re-sources/ckd-national-facts.D

  3. Staufer M, Prevalence of Anemia in Chronic Kidney Disease in the Unites States, Plos
    One, 2014, https://doi.org/10.1371/journal.pone.0084943