DIAGNOSIS OF IRON DEFICIENCY ANEMIA IN
NON-DIALYSIS-DEPENDENT CHRONIC KIDNEY DISEASE
The World Health Organization defines anemia as a hemoglobin (Hb) concentration of <12.0 g/dL in women and <13.0 g/dL in men
Diagnosis Considerations 3
A focused clinical assessment is required for an initial assessment of anemia in CKD.
Although relative erythropoietin deficit will typically be the main contributing factor, other causes should also be taken into account.
It is important to undertake a focused history, physical exam, and lab review.
As in anemia without kidney disease, a thorough search for indications of decreased erythrocyte production, hemolysis, sequestration, and bleeding is required.
Testing for occult blood loss and iron deficiency in individuals with CKD should be prioritized due to the high prevalence of these conditions in this population.
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- National Heart, Lung, and Blood Institute. Iron-deciency Anemia. Date updated March 2022. Date accessed August 2022. https://www.nhlbi.nih.gov/health/anemia/iron-deciency-anemia
National Institute of Diabetes and Digestive and Kidney Diseases. Chronic Kidney Diseases Tests and Diagnosis. Date accessed August 2022. https://www.niddk.nih.gov/health-information/kidney-dis-